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methylation epic beadchip 850k array  (Illumina Inc)


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    Illumina Inc methylation epic beadchip 850k array
    Methylation Epic Beadchip 850k Array, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 96/100, based on 1186 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/methylation+array/Infinium+MethylationEPIC+BeadChip+Kit/pm41841374-35-25-30
    Average 96 stars, based on 1186 article reviews
    methylation epic beadchip 850k array - by Bioz Stars, 2026-10
    96/100 stars

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    Related Articles

    Methylation:

    Article Title: A Rapid and Reliable Test for BRCA1 Promoter Hypermethylation in Paraffin Tissue Using Pyrosequencing
    Article Snippet: .. To establish the accuracy of this assay, we selected twenty (20) HGSC cases that were analyzed for methylation events using the Illumina methylation array as part of TCGA project [ ] or using a BRCA1 methylation analysis by a real-time PCR assay as part of this study. ..

    Article Title: Radiogenomic method combining DNA methylation profiles and magnetic resonance imaging radiomics predicts patient prognosis in skull base chordoma.
    Article Snippet: .. Validation of the generalizability of DNA methylation signature 4 across different datasets To assess the generalizability of Signature 4 across different datasets, we employed a methylation validation cohort consisting of 14 patients with FFPE tissue analyzed using the Illumina EPIC methylation array. ..

    Article Title: Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancer.
    Article Snippet: .. Briefly, we identified genes with single occupancy of at least one of SUZ12, EED, or H3K27me28 (n = 1591) and filtered CpGs within 200 bp of their transcription start site using the Illumina methylation array manifest (n = 1343). ..

    Article Title: A Rapid and Reliable Test for BRCA1 Promoter Hypermethylation in Paraffin Tissue Using Pyrosequencing
    Article Snippet: In this study, we present the validation of a pyrosequencing method for assessing BRCA1 promoter methylation. .. We identified twenty (20) HGSC cases that were previously analyzed as part of The Cancer Genome Atlas (TCGA) project [ ] for methylation events using the Illumina methylation array (Illumina, San Diego, CA, USA), or for BRCA1 methylation analysis by a real-time PCR assay developed by our research team at Memorial Sloan Kettering Cancer Center (MSKCC) as part of other ongoing laboratory studies. ..

    Article Title: Setd1a Loss-of-function Disrupts Epigenetic Regulation of Ribosomal Genes via Altered DNA Methylation.
    Article Snippet: .. The Illumina methylation array covers a subset of DNA methylation sites, and it is likely that some genotype-associated differences could have been missed. ..

    Article Title: A cross-generational methylomic signature of infant maltreatment in newborn rhesus macaques.
    Article Snippet: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record.. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article.. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

    Article Title: Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancer
    Article Snippet: .. Briefly, we identified genes with single occupancy of at least one of SUZ12, EED, or H3K27me ( n = 1591) and filtered CpGs within 200 bp of their transcription start site using the Illumina methylation array manifest ( n = 1343). ..

    Real-time Polymerase Chain Reaction:

    Article Title: A Rapid and Reliable Test for BRCA1 Promoter Hypermethylation in Paraffin Tissue Using Pyrosequencing
    Article Snippet: .. To establish the accuracy of this assay, we selected twenty (20) HGSC cases that were analyzed for methylation events using the Illumina methylation array as part of TCGA project [ ] or using a BRCA1 methylation analysis by a real-time PCR assay as part of this study. ..

    Article Title: A Rapid and Reliable Test for BRCA1 Promoter Hypermethylation in Paraffin Tissue Using Pyrosequencing
    Article Snippet: In this study, we present the validation of a pyrosequencing method for assessing BRCA1 promoter methylation. .. We identified twenty (20) HGSC cases that were previously analyzed as part of The Cancer Genome Atlas (TCGA) project [ ] for methylation events using the Illumina methylation array (Illumina, San Diego, CA, USA), or for BRCA1 methylation analysis by a real-time PCR assay developed by our research team at Memorial Sloan Kettering Cancer Center (MSKCC) as part of other ongoing laboratory studies. ..

    Biomarker Discovery:

    Article Title: Radiogenomic method combining DNA methylation profiles and magnetic resonance imaging radiomics predicts patient prognosis in skull base chordoma.
    Article Snippet: .. Validation of the generalizability of DNA methylation signature 4 across different datasets To assess the generalizability of Signature 4 across different datasets, we employed a methylation validation cohort consisting of 14 patients with FFPE tissue analyzed using the Illumina EPIC methylation array. ..

    DNA Methylation Assay:

    Article Title: Radiogenomic method combining DNA methylation profiles and magnetic resonance imaging radiomics predicts patient prognosis in skull base chordoma.
    Article Snippet: .. Validation of the generalizability of DNA methylation signature 4 across different datasets To assess the generalizability of Signature 4 across different datasets, we employed a methylation validation cohort consisting of 14 patients with FFPE tissue analyzed using the Illumina EPIC methylation array. ..

    Article Title: Setd1a Loss-of-function Disrupts Epigenetic Regulation of Ribosomal Genes via Altered DNA Methylation.
    Article Snippet: .. The Illumina methylation array covers a subset of DNA methylation sites, and it is likely that some genotype-associated differences could have been missed. ..

    Formalin-fixed Paraffin-Embedded:

    Article Title: Radiogenomic method combining DNA methylation profiles and magnetic resonance imaging radiomics predicts patient prognosis in skull base chordoma.
    Article Snippet: .. Validation of the generalizability of DNA methylation signature 4 across different datasets To assess the generalizability of Signature 4 across different datasets, we employed a methylation validation cohort consisting of 14 patients with FFPE tissue analyzed using the Illumina EPIC methylation array. ..

    other:

    Article Title: A Rapid and Reliable Test for BRCA1 Promoter Hypermethylation in Paraffin Tissue Using Pyrosequencing.
    Article Snippet: We identified twenty (20) HGSC cases that were previously analyzed as part of The Cancer Genome Atlas (TCGA) project [9] for methylation events using the Illumina methyla- tion array (Illumina, San Diego, CA, USA), or for BRCA1 methylation analysis by a real-time PCR assay developed by our research team at Memorial Sloan Kettering Cancer Center (MSKCC) as part of other ongoing laboratory studies.



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    INFINIUM Inc custom infinium methylation array horvathmammalmethylchip40
    ( A ) Epigenome-wide association study of dpi in PBMCs based on the entire <t>methylation</t> array. The volcano plots display the −log 10 ( P values) and the directionality of association between CpG sites and infection stages (A, EC, and LC) compared with B: A versus B (left panel), EC versus B (center panel), and LC versus B (right panel). Each dot represents a specific DNAme site. Shown are significantly associated CpG sites ( q < 0.05) with hypomethylation (blue), hypermethylation (red), and nonsignificant (gray). The horizontal axis represents the mean methylation change (i.e., the difference between group means), and the vertical axis represents −log 10 ( P values). ( B ) Changes in EA during each infection stage (A, EC, and LC) relative to B. Biological age analysis was performed based on subsets of clock CpGs. EA at the 3 infection time points was compared with B using mixed-effects linear regression modeling of longitudinal EA changes in PBMCs based on 10 epigenetic clocks. The results are shown separately for young (right) and old (left) RMs. Epigenetic age changes in young (blue) and old (red) RMs are shown. Saturated colors indicate statistically significant changes ( P < 0.05); pale colors indicate nonsignificant changes ( P > 0.05). A statistically significant increase in EA was observed only in young RMs. B–H, Benjamini–Hochberg correction; DMP, differentially methylated positions; dpi, days after infection; RMs, rhesus macaques; B, baseline; A, acute; EC, early chronic; LC, late chronic; EA, epigenetic age.
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    Image Search Results


    ( A ) Epigenome-wide association study of dpi in PBMCs based on the entire methylation array. The volcano plots display the −log 10 ( P values) and the directionality of association between CpG sites and infection stages (A, EC, and LC) compared with B: A versus B (left panel), EC versus B (center panel), and LC versus B (right panel). Each dot represents a specific DNAme site. Shown are significantly associated CpG sites ( q < 0.05) with hypomethylation (blue), hypermethylation (red), and nonsignificant (gray). The horizontal axis represents the mean methylation change (i.e., the difference between group means), and the vertical axis represents −log 10 ( P values). ( B ) Changes in EA during each infection stage (A, EC, and LC) relative to B. Biological age analysis was performed based on subsets of clock CpGs. EA at the 3 infection time points was compared with B using mixed-effects linear regression modeling of longitudinal EA changes in PBMCs based on 10 epigenetic clocks. The results are shown separately for young (right) and old (left) RMs. Epigenetic age changes in young (blue) and old (red) RMs are shown. Saturated colors indicate statistically significant changes ( P < 0.05); pale colors indicate nonsignificant changes ( P > 0.05). A statistically significant increase in EA was observed only in young RMs. B–H, Benjamini–Hochberg correction; DMP, differentially methylated positions; dpi, days after infection; RMs, rhesus macaques; B, baseline; A, acute; EC, early chronic; LC, late chronic; EA, epigenetic age.

    Journal: The Journal of Clinical Investigation

    Article Title: Pathogenic SIV infection is associated with acceleration of epigenetic age in rhesus macaques

    doi: 10.1172/JCI189574

    Figure Lengend Snippet: ( A ) Epigenome-wide association study of dpi in PBMCs based on the entire methylation array. The volcano plots display the −log 10 ( P values) and the directionality of association between CpG sites and infection stages (A, EC, and LC) compared with B: A versus B (left panel), EC versus B (center panel), and LC versus B (right panel). Each dot represents a specific DNAme site. Shown are significantly associated CpG sites ( q < 0.05) with hypomethylation (blue), hypermethylation (red), and nonsignificant (gray). The horizontal axis represents the mean methylation change (i.e., the difference between group means), and the vertical axis represents −log 10 ( P values). ( B ) Changes in EA during each infection stage (A, EC, and LC) relative to B. Biological age analysis was performed based on subsets of clock CpGs. EA at the 3 infection time points was compared with B using mixed-effects linear regression modeling of longitudinal EA changes in PBMCs based on 10 epigenetic clocks. The results are shown separately for young (right) and old (left) RMs. Epigenetic age changes in young (blue) and old (red) RMs are shown. Saturated colors indicate statistically significant changes ( P < 0.05); pale colors indicate nonsignificant changes ( P > 0.05). A statistically significant increase in EA was observed only in young RMs. B–H, Benjamini–Hochberg correction; DMP, differentially methylated positions; dpi, days after infection; RMs, rhesus macaques; B, baseline; A, acute; EC, early chronic; LC, late chronic; EA, epigenetic age.

    Article Snippet: DNAme profiles were generated using a custom Infinium methylation array (HorvathMammalMethylChip40) representing 37,492 CpG highly conserved sites in the mammals, with the NCBI’s Gene Expression Omnibus (GEO) accession number GPL28271 for microarray design ( ).

    Techniques: Methylation, Infection